Table 4.
Association between esophageal cancer risk and the p53, GSTP1 polymorphisms, stratified by ethnicity.
| SNP site | Studies of available& | No. of Cases | No. of Controls | OR# | 95%CI | P* |
|---|---|---|---|---|---|---|
| p53 Arg72Pro | ||||||
| Asian | 22,24,25 | 1052 | 2063 | 1.35 | 1.14-1.60 | 0.09 |
| Mix | 19,23,27 | 1868 | 2011 | 1.04 | 0.86-1.25 | 0.60 |
| GSTP1 Ile105Val | ||||||
| Asian | 22,25,29,31,32 | 641 | 1415 | 0.99 | 0.66-1.49 | 0.00 |
| Caucasian | 19,20,30,33 | 1768 | 1970 | 1.06 | 0.86-1.31 | 0.02 |
# The OR was obtained in dominant genetic model.
* Test for heterogeneity. Fixed-effects model was used when P value for heterogeneity test > 0.05; otherwise, random-effects model was used.
& Studies of available was referred to the reference resource of the stratified variable, which data was available.