Skip to main content
. Author manuscript; available in PMC: 2011 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2010 Jun 23;80(8):1115–1124. doi: 10.1016/j.bcp.2010.06.013

Table 2.

Current IGFBP 3D structures and their complexes with IGF-1

Protein Structural
Domain		 Complex Experimental
Method		 PDB
code
IGFBP-1 C-domain Uncomplexed X-ray 1ZT3,
1ZT5
IGFBP-2 C-domain Uncomplexed NMR 2H7T
IGFBP-4 N-domain Complex with
IGF-1		 X-ray 2DSP
1WQJ
Ternary complex
with IGF-1 and
C- domain of
IGFBP-1		 X-ray 2DSQ
N- and C-domain Ternary complex
with IGF-1		 X-ray 2DSR
IGFBP-5 N-domain
(Residues 58–111)		 Complex with
IGF-1		 X-ray 1H59
N-domain
(Residues 40–92)		 Uncomplexed NMR 1BOE
IGFBP-6 N-domain
(Residues 25–69)		 Uncomplexed NMR 2JM2
C-domain Uncomplexed NMR 1RMJ