Table 1.
Characteristics of up- and down-states in RS, FS, and GIN cells
| RS | FS | GIN | |
|---|---|---|---|
| Number of cells | 20 | 12 | 21 |
| Input resistance, MΩ* | 190 ± 17 | 114 ± 7 | 225 ± 25 |
| Number of up-states analyzed | 436 | 254 | 333 |
| up-state duration (ms) | 3354 ± 225 | 3772 ± 370 | — |
| down-state membrane potential, mV† | −68.1 ± 1.1 | −65.8 ± 1.6 | −58.7 ± 1.2 |
| up-state membrane potential, mV† | −56.2 ± 0.8 | −60.2 ± 0.6 | −54.3 ± 0.7 |
| down-state firing frequency, Hz‡ | — | — | 6.4 ± 1.7 |
| up-state firing frequency, Hz‡ | 10.3 ± 1.2 | 30.6 ± 2.6 | 11.0 ± 1.6 |
All data are medians ± SE.
*
FS vs. all others P < 0.01; RS and GIN not significantly different from one another, P > 0.6.
†
RS-down vs. RS-up: P < 1 × 10−5: FS-down vs. FS-up: P < 0.01; GIN-down vs. GIN-up: P < 0.05.
‡
All values in these two rows different from one another (P < 0.02), except RS up and GIN up (P = 0.6). RS, regular spiking; FS, fast spiking; GIN, GFP-(and somatostatin-) expressing inhibitory neurons.