Fig. 6.
The PLCβ inhibitor, ET-18-OCH3, did not block DA's effects on LP IA. IA was measured before and during a 10 min, 10−5 M DA application, after a 30 min washout, and after sequential 10 min applications of 10−5 M ET-18-OCH3 and ET-18-OCH3+DA. Measurements from the 1st recording served as baseline for DA and washout comparisons. The washout measurements served as baseline for all subsequent drug applications. The change from baseline was plotted for V1/2 activation (A) and V1/2 inactivation (B). *, significant differences from baseline as determined with 1 way ANOVAs followed by Tukey post hoc tests.