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Drug-free [DA]max responses after 1-day saline or cocaine followed by 24-h withdrawal. A: experimental timeline for 1-day drug-exposure and fast-scan cyclic voltammetry (FSCV) recordings. B and C: pre-exposure to 1-day cocaine did not alter peak dopamine responses in the NAc core or shell compared with 1-day saline-treated subjects. [DA]max in the NAc core (n = 9) (B) and NAc shell (n = 16) (C) after 10-, 20-, 40-, and 60-Hz stimulations of the VTA. [DA]max data presented as ±SE.
