TABLE 1.
Antibiotic | No.a (%; n = 4,863) | No. (%) receiving: |
OR (95% CI) | P | |
---|---|---|---|---|---|
Combination therapy (n = 678) | β-Lactam only (n = 4,185) | ||||
Ampicillin | 380 (8) | 43 (6) | 377 (8) | 0.8 (0.5-1.1) | 0.1 |
Amoxicillin-clavulanate | 249 (5) | 3 (0.4) | 246 (6) | 0.1 (0.02-0.2) | <0.0001 |
Non-antipseudomonal cephalosporin | 2,490 (51) | 117 (17) | 2,373 (57) | 0.2 (0.1-0.3) | <0.0001 |
Antipseudomonal cephalosporin | 354 (7) | 186 (27) | 168 (4) | 9 (7-11) | <0.0001 |
Piperacillin-tazobactam | 979 (20) | 156 (23) | 863 (20) | 1.2 (1-1.5) | 0.04 |
Antipseudomonal carbapenem | 761 (16) | 185 (27) | 576 (14) | 2.4 (2-3) | <0.0001 |
In 350 episodes, more than one β-lactam was administered(ampicillin plus a cephalosporin in 76% of these cases).