TABLE 5.
Resistance genes and phenotypes of sequenced pSK41-like plasmids
| Gene(s) | Phenotypic resistance | Presencea in the following plasmid: |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| pSK41 (46.4 kb) | pGO1 (54 kb) | pLW043 (57.9 kb) | pUSA03 (37.1 kb) | pV030-8 (39 kb) | pTN147 (43.9 kb) | pGA672 (47.3 kb) | pPAnicu (44.1 kb) | ||
| aac6′-aph2″ | Gentamicin, tobramycin, kanamycin | X | X | X | X | X | X | ||
| aadD | Neomycin | X | X | X | X | X | |||
| qacA, qacB, smr | Quaternary ammonium compounds | X | X | X | X | X | |||
| dfrA | Trimethoprim | X | X | X | |||||
| vanA | Vancomycin | X | |||||||
| mupA | Mupirocin | X | X | X | X | X | |||
| ermC | Macrolides-lincosamides-streptogramins | X | |||||||
| blaZ | β-Lactams | X | |||||||
| bleO | Bleomycin | X | X | X | |||||
a
An X indicates the presence of a gene. The source or reference for each plasmid is given in parentheses as follows: pSK41 (4), pGO1 (5), pLW043 (36), pUSA03 (11), pV030-8 (GenBank accession number NC_010279), pTN147 (this study; GenBank accession number GQ900433.1), pGA672 (this study; GenBank accession number GQ900432.1), and pPAnicu (this study; GenBank accession number GQ900434.1).