TABLE 4.

Susceptibilities of PAO1 and ampD and dacB null mutants to PIP, ATM, and CAZ in the presence or absence of PUGNAc^a

Strain	MICb (μg/ml)
	PIP			ATM			CAZ
	−I	+I (0.5 mM)	+I (5 mM)	−I	+I (0.5 mM)	+I (5 mM)	−I	+I (0.5 mM)	+I (5 mM)
PAO1	4	4	4	3	3	3	2	2	2
PAΔD	48	24	24	6	3	3	8	4	4
PAΔdB	64	32	24	12	4	3	24	8	6
PAdacBΔD	384	256	256	32	32	24	96	64	64

^aThe bacterial strains were treated with (+I) the NagZ inhibitor PUGNAc at 0.5 mM and 5 mM concentrations or were not treated (−I) (39).

^bThe MIC was determined by the broth microdilution method (8). All measurements were performed in triplicate.