TABLE 1.

Comparison of MICs of T-2307 and other antifungal agents against C. glabrata ATCC 90030 determined in various media

Antifungal agent	MIC (μg/ml)
	Glucoseb					0.2% glycerolc	0.2% Glucose + Alamar blue
	2%	0.2%a	0.1%	0.05%	0.02%		24 h	48 h
T-2307	>0.125	0.0039	0.0039	0.001	0.001	0.0005	0.0156	>0.125
Fluconazole	16	8	8	8	4	4	8	16
Micafungin	0.0625	0.0625	0.0625	0.0625	0.125	0.125	0.0625	0.0625
Amphotericin B	2	2	2	2	2	1	1	2

^aEquivalent to the amount used in the CLSI method.

^bIncubation for 48 h except with micafungin (incubation for 24 h).

^cIncubation for 48 h.