TABLE 1.

Summary of absolute and normalized IC₅₀ values for mutant and control lines

Drug	Measurement	Value (mean ±SEM)
		7G8a		D10b
		L263	263E	L263	263E
Artemisinin	Absolute IC50 (nM)	20.7 ± 2.9	22.3 ± 1.7	42.8 ± 5.0	51.6 ± 5.5
	Normalized IC50	1.00 ± 0.11	1.30 ± 0.12	1.00 ± 0.12	1.20 ± 0.13
	No. of assays	12	28	11	21
Dihydroartemisinin	Absolute IC50 (nM)	2.26 ± 0.29	2.37 ± 0.18	3.41 ± 0.36	3.96 ± 0.35
	Normalized IC50	1.00 ± 0.10	1.33 ± 0.13	1.00 ± 0.11	1.18 ± 0.10
	No. of assays	12	28	13	27
Artesunate	Absolute IC50 (nM)	13.5 ± 1.7	14.9 ± 1.4	23.6 ± 3.1	26.2 ± 2.8
	Normalized IC50	1.00 ± 0.09	0.97 ± 0.07	1.00 ± 0.09	0.99 ± 0.08
	No. of assays	12	28	13	27

^a7G8 L263 refers to C1^7G8 and C2^7G8; 7G8 263E refers to M1^7G8, M2^7G8, M3^7G8, and M4^7G8.

^bD10 L263 refers to C1^D10 and C2^D10; D10 263E refers to M1^D10, M2^D10, and M3^D10.