TABLE 1.
Patient characteristics at baseline
| Variable | Valuea |
|
|---|---|---|
| AS/MQ fixed (n = 25) | AS + MQ nonfixed (n = 25) | |
| Age (yr) | 26.6 (17-50) | 28.9 (16-45) |
| Wht (kg)b | 50 (40-62) | 51.0 (40-65) |
| Male/Female [no. (%)] | 19 (76)/6 (24) | 22 (88)/3 (12) |
| Burmese (no.) | 13 | 14 |
| Karen (no.) | 7 | 8 |
| Mon (no.) | 4 | 3 |
| Thai (no.) | 1 | 0 |
| Tempb (°C) | 38.5 (37.3-40) | 38.1 (37-40) |
| Pulse beatsb/minute | 90 (72-118) | 90 (76-124) |
| Supine blood pressureb (mm Hg) | 110 (90-130)/70 (60-90) | 110 (90-130)/70 (60-80) |
| Palpable spleen [no. (%)] | 0 | 0 |
| Palpable liver [no. (%)] | 3 (12) | 4 (16) |
| Asexual parasitemiab/μl | 30,816 (69-170,800) | 28,231 (20-140,280) |
| Gametocyte carriage [no. (%)] | 3 (12.5) | 6 (25) |
| Hb (g/dl) | 12.58 (10.3-17) | 12.05 (8.7-15.5) |
| Total white cell count × 109/liter | 5.72 (1.5-9.2) | 5.04 (2-10.1) |
| Neutrophils × 109/liter | 3.67 (0.7-6.9) | 3.15 (1.1-6.1) |
| Lymphocytes × 109/liter | 1.45 (0.5-3.4) | 1.34 (0.4-4.0) |
| Eosinophils × 109/liter | 0.13 (0-0.4) | 0.15 (0-0.7) |
| Monocytes × 109/liter | 0.39 (0.1-0.8) | 0.34 (0.1-0.8) |
| Platelet count × 109/literb | 85 (19-334) | 99 (28-239) |
| Creatinine (mg/dl) | 0.87 (0.5-1.2) | 0.84 (0.4-1.3) |
| AST (IU/liter) | 24.7 (11-44) | 32.2 (12-111) |
| ALT (IU/liter) | 20.9 (9-48) | 30 (3-113) |
| Total bilirubin (mg/dl) | 1.36 (0.5-2.5) | 1.32 (0.4-2.8) |
| Dose of AS (mg/kg)b | 4 (3.2-5) | 4 |
| Dose of MQ (mg/kg)b | 8 (6.5-10) | 15 and 10 |
a
All continuous data are reported as mean (range) unless otherwise indicated.
b
Median (range).