TABLE 3.
Percentages of isolates included in each category (susceptible, susceptible/dose dependent, or resistant) by each procedure (CLSI and Etest) for the MICs of voriconazole and fluconazole
| Species | Procedure | % of MICs in each categorya |
|||||
|---|---|---|---|---|---|---|---|
| Voriconazole |
Fluconazole |
||||||
| S | SDD | R | S | SDD | R | ||
| D. capitatus | CLSI | 100 | 0 | 0 | 85.7 | 14.3 | 0 |
| Etest | 100 | 0 | 0 | 100 | 0 | 0 | |
| R. mucilaginosa | CLSI | 33.3 | 44.4 | 22.2 | 0 | 0 | 100 |
| Etest | 0 | 0 | 100 | 0 | 0 | 100 | |
| S. cerevisiae | CLSI | 100 | 0 | 0 | 80 | 20 | 0 |
| Etest | 100 | 0 | 0 | 80 | 5 | 15 | |
| Trichosporon spp. | CLSI | 83.8 | 10.8 | 5.4 | 66.2 | 9.5 | 24.3 |
| Etest | 75.7 | 0 | 24.3 | 70.3 | 1.4 | 28.4 | |
| Total | CLSI | 83.8 | 10.8 | 5.4 | 66.2 | 9.5 | 24.3 |
| Etest | 75.7 | 0 | 24.3 | 70.3 | 1.4 | 28.4 | |
a
Percentages of CLSI and Etest MICs that were within the Candida breakpoints chosen for fluconazole (MICs of ≤8 μg/ml, susceptible [S]; MICs of 16 to 32 μg/ml, susceptible/dose dependent [SDD]; MICs of ≥64 μg/ml, resistant [R]) and voriconazole (MICs of ≤1 μg/ml, S; MICs of 2 μg/ml, SDD; MICs of ≥4 μg/ml, R) (2, 10).