Fig. 1.
Protein immunoblot analysis of AC1 and AC8 expression in the developing striatum. Abundant protein expression of both AC1 and AC8 was detected in membrane-enriched striatal protein extracts obtained from P7 WT and DKO mice. A single immunoreactive band at ~123 kD, representing AC1 protein was detected in all WT but not DKO samples. A single immunoreactive band at ~135 kD, representing AC8 protein was detected in all WT but not DKO samples. Equal loading conditions were verified by immunodetection for binding protein (BiP).