Table 1.
Brain structure | Density | |||
---|---|---|---|---|
vehicle | sst2 agonist | ODT8- SST |
||
(n=5) | (n=6) | (n=6) | ||
Forebrain | Piriform cortex | + | ++ | + |
Insular cortex | − | ++ | − | |
Entorhinal cortex | + | ++ | + | |
Cingulate cortex | − | + | + | |
Somatomotor cortex | + | ++ | + ~ ++ | |
Lateral septum | − | + | − | |
Striatum | − | ++ | − | |
other cortical areas | + | ++ | + | |
Anterior cortical amygdaloid nucleus | − | + | + | |
Medial amygdaloid nucleus | + | + | + | |
Central amygdaloid nucleus | − | − | − | |
Basolateral amygdaloid nucleus | − | +++ | ++ | |
Hypothalamus | Lateral preoptic area | − ~ + | + | − |
Suprachiasmatic nucleus (Cap) | + | + | + | |
Supraoptic nucleus | − | ++++ | +++ | |
Accessory neurosecretory nuclei | − | + | + | |
Paraventricular nucleus | ||||
Parvicellular anterior | − | − | − | |
Parvicellular medial | − | − ~ + | − | |
Ventral | − | − | − | |
Magnocellular medial | − | +++ | ++ | |
Magnocellular lateral | − | +++ | ++ | |
Posterior | − | − ~ + | − | |
Medial hypothalamic area | + | + | − | |
Dorsomedial hypothalamic nucleus | + | ++ | − | |
Arcuate nucleus | − | ++ | − | |
Ventral tuberomammillary nucleus | − | +++ | + | |
Premamillary nucleus, ventral part | − | ++ | ++ | |
Thalamus | Paraventricular thalamic nucleus, anterior part | + | + | − |
Parasubthalamic nucleus | − | ++ | − | |
Cerebellum | Cerebellar cortex | − | ++ | + |
Midbrain | Periaqueductal Gray | + | + | − ~ + |
Superior and inferior colliculi | ++ | ++ | + | |
Pons | Pontine nuclei | ++ | ++ | + |
External subnucleus of lateral parabrachial nucleus | − | ++ ~ +++ | + | |
Medulla | Raphe pallidus | − | + | − ~ + |
Area postrema | − | − | + | |
Lateral reticular nucleus | + | − | − ~ + | |
Medullary reticular nucleus, dorsal part | − | ++ | + | |
Spinal trigeminal nucleus, superficial layer | − | +++ | ++ | |
Inferior olivary nucleus | − | ++ | + |
Density: “+” approximately 1–4 cells, “++” 5–10, “+++” 10–20 and “++++” >20 immunoreactive cells in a 100 µm×100 μm area of an ocular grid when the objective was 10×.