Table 1.

Rat brain structures showing Fos immunoreactivity following icv injection of vehicle, sst₂ agonist or ODT8-SST. Brain regions that do not express Fos immunoreactivity are omitted from the table.

	Brain structure	Density
		vehicle	sst2 agonist	ODT8- SST
		(n=5)	(n=6)	(n=6)
Forebrain	Piriform cortex	+	++	+
	Insular cortex	−	++	−
	Entorhinal cortex	+	++	+
	Cingulate cortex	−	+	+
	Somatomotor cortex	+	++	+ ~ ++
	Lateral septum	−	+	−
	Striatum	−	++	−
	other cortical areas	+	++	+
	Anterior cortical amygdaloid nucleus	−	+	+
	Medial amygdaloid nucleus	+	+	+
	Central amygdaloid nucleus	−	−	−
	Basolateral amygdaloid nucleus	−	+++	++
Hypothalamus	Lateral preoptic area	− ~ +	+	−
	Suprachiasmatic nucleus (Cap)	+	+	+
	Supraoptic nucleus	−	++++	+++
	Accessory neurosecretory nuclei	−	+	+
	Paraventricular nucleus
	Parvicellular anterior	−	−	−
	Parvicellular medial	−	− ~ +	−
	Ventral	−	−	−
	Magnocellular medial	−	+++	++
	Magnocellular lateral	−	+++	++
	Posterior	−	− ~ +	−
	Medial hypothalamic area	+	+	−
	Dorsomedial hypothalamic nucleus	+	++	−
	Arcuate nucleus	−	++	−
	Ventral tuberomammillary nucleus	−	+++	+
	Premamillary nucleus, ventral part	−	++	++
Thalamus	Paraventricular thalamic nucleus, anterior part	+	+	−
	Parasubthalamic nucleus	−	++	−
Cerebellum	Cerebellar cortex	−	++	+
Midbrain	Periaqueductal Gray	+	+	− ~ +
	Superior and inferior colliculi	++	++	+
Pons	Pontine nuclei	++	++	+
	External subnucleus of lateral parabrachial nucleus	−	++ ~ +++	+
Medulla	Raphe pallidus	−	+	− ~ +
	Area postrema	−	−	+
	Lateral reticular nucleus	+	−	− ~ +
	Medullary reticular nucleus, dorsal part	−	++	+
	Spinal trigeminal nucleus, superficial layer	−	+++	++
	Inferior olivary nucleus	−	++	+

Density: “+” approximately 1–4 cells, “++” 5–10, “+++” 10–20 and “++++” >20 immunoreactive cells in a 100 µm×100 μm area of an ocular grid when the objective was 10×.