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. Author manuscript; available in PMC: 2010 Sep 7.
Published in final edited form as: RNA Biol. 2009 Sep 24;6(4):426–433. doi: 10.4161/rna.6.4.8841

Table 4.

Top aberrantly expressed RBPs in tumor and cancer related processes

Biological process Connectivity Genes
Apoptosis 19 ACO1, ADAR, AKAP1, APOBEC1, NKRF, NOL8, NPM1, PABPC4, PNPT1, PTBP1, PUF60, RBM10, RBM25, RPL7, RPS5, SSB, TACC1, TIA1, TROVE2
Cell cycle 19 ADAR, AKAP1, CSTF2, CSTF3, EIF3B, FUS, GARS, MARS, NONO, NPM1, PNPT1, PSMA1, PTBP1, RBM14, RPL7, RPS5, SLBP, SSB, TACC1
Cell differentiation 15 ACO1, ADAR, APOBEC1, CSTF2, EIF3G, FUS, GARS, KHSRP, NONO, NPM1, PNPT1, PTBP1, RBM14, RPS5, SNRPA
Cell proliferation 14 ACO1, ADAR, APOBEC1, CPSF6, CSTF2, EIF3B, NKRF, NPM1, PTBP1, RBM14, RBMX, SLBP, SSB, TACC1
Cell growth 10 ADAR, CSTF2, FXR1, NCBP2, NOL8, NPM1, PNPT1, RBM8A, RPL18, STRBP
Cell survival 8 ACO1, ADAR, AKAP1, NONO, NPM1, TACC1, TIA1, TROVE2

We used Pathway Studio 6 to identify connections between the selected RBPs and cancer related processes. Proteins are listed according to references that indicate participation in specific cellular functions.