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. 2010 Sep 7;5(9):e12170. doi: 10.1371/journal.pone.0012170

Figure 3. Effects of olprinone on MPO activity and superfamily of adhesion molecules.

Figure 3

Following the injury, MPO activity in spinal cord from SCI mice was significantly increased at 24 h after the damage in comparison to sham groups (A). In addition, at 24 h after SCI, a positive immunohistochemical staining for ICAM-1 (C) and for P-selectin (F) was found in spinal cord sections compared to sham-operated mice (B and E, respectively). The positive immunostaining for ICAM-1 and for P-selectin was significantly decreased in sections from mice treated with olprinone (0,2 mg/kg) (D and G, respectively).