Figure 5. Rac GTPase Activation is Critical for Enhanced Oxidative Damage in the Hippocampus CA1 Following GCI.
DAB staining of representative coronal CA1 sections show NSC23766 ability to attenuate staining for oxidative stress markers for lipid peroxidation (4-HNE), DNA damage (8-OHdG) and histone phosphorylation (p-H2A.X). (Four to five animals per treatment group, magnification used was 20X).