Fig. 1.

Reaction graphs of the Michaelis–Menten enzymatic reaction, either complete with intermediary complex SE, or reduced with or without enzyme E. The first reduction can be achieved with the graphical operations explained in Section 2.2, for example by merging the reaction nodes rule_1 and rule_3 in pink into a reaction node rule and by deleting the green nodes SE and rule_2. The second reduction simply deletes the blue node E.