Table 1.
Selected GO categories for various modules of the prostate cancer network inferred in this study
| Module ID | Ng | GO category | Corrected P-value | Description |
|---|---|---|---|---|
| 0 | 59 | GO:0043170 | 1.45E-02 | Macromolecule metabolic process |
| GO:0006374 | 1.45E-02 | Nuclear mRNA splicing | ||
| GO:0006395 | 1.45E-02 | RNA splicing | ||
| GO:0006397 | 1.45E-02 | mRNA processing | ||
| GO:0008152 | 3.21E-02 | Metabolic process | ||
| GO:0022402 | 3.62E-02 | Cell cycle process | ||
| 2 | 54 | GO:0048002 | 3.68E-03 | Antigen processing and presentation of peptide antigen |
| GO:0006955 | 1.55E-02 | Immune response | ||
| GO:0002376 | 1.56E-02 | Immune system process | ||
| GO:0008283 | 4.05E-02 | Cell proliferation | ||
| 4 | 46 | GO:0007067 | 8.42E-24 | Mitosis |
| GO:0007049 | 2.42E-20 | Cell cycle | ||
| GO:0022402 | 2.51E-17 | Cell cycle process | ||
| GO:0000074 | 9.25E-09 | Regulation of cell cycle | ||
| GO:0000075 | 2.30E-07 | Cell cycle checkpoint | ||
| GO:0008283 | 1.77E-04 | Cell proliferation | ||
| 7 | 29 | GO:0009615 | 4.72E-05 | Response to virus |
| GO:0051707 | 7.30E-04 | Response to other organism | ||
| GO:0006955 | 8.23E-04 | Immune response | ||
| GO:0009607 | 1.92E-03 | Response to biotic stimulus | ||
| GO:0002376 | 3.31E-03 | Immune system process | ||
| 8 | 46 | GO:0007243 | 4.55E-04 | Protein kinase cascade |
| GO:0006950 | 6.85E-04 | Response to stress | ||
| GO:0006915 | 2.60E-03 | Apoptosis | ||
| GO:0012501 | 2.60E-03 | Programmed cell death | ||
| GO:0007242 | 1.16E-02 | Intracellular signaling cascade | ||
| 11 | 42 | GO:0000245 | 3.67E-03 | Spliceosome assembly |
| GO:0000074 | 2.37E-02 | Regulation of cell cycle | ||
| GO:0048523 | 2.37E-02 | Negative regulation of cellular process | ||
| GO:0006374 | 2.37E-02 | Nuclear mRNA splicing | ||
| 12 | 31 | GO:0007154 | 2.85E-03 | Cell communication |
| GO:0007165 | 3.60E-03 | Signal transduction | ||
| GO:0045767 | 9.42E-03 | Regulation of anti-apoptosis | ||
| GO:0007242 | 3.73E-02 | Intracellular signaling cascade | ||
| 14 | 16 | GO:0006066 | 1.06E-02 | Alcohol metabolic process |
| GO:0019318 | 1.37E-02 | Hexose metabolic process | ||
| GO:0005996 | 1.37E-02 | Monosaccharide metabolic process | ||
| GO:0005975 | 2.19E-02 | Carbohydrate metabolic process | ||
| GO:0002252 | 3.62E-02 | Immune effector process | ||
| 18 | 13 | GO:0006334 | 4.74E-19 | Nucleosome assembly |
| GO:0031497 | 7.18E-19 | Chromatin assembly | ||
| GO:0006323 | 6.53E-18 | DNA packaging | ||
| GO:0006333 | 7.42E-18 | Chromatin assembly or disassembly | ||
| GO:0006952 | 6.54E-03 | Defense response | ||
| 21 | 9 | GO:0019882 | 1.30E-14 | Antigen processing and presentation |
| GO:0006955 | 3.38E-10 | Immune response | ||
| 22 | 23 | GO:0006416 | 7.53E-09 | Translation |
| GO:0010467 | 6.55E-05 | Gene expression | ||
| 29 | 32 | GO:0008652 | 3.08E-04 | Amino acid biosynthetic process |
| GO:0019752 | 6.73E-04 | Carboxylic acid metabolic process | ||
| 38 | 11 | GO:0007010 | 1.22E-02 | Cytoskeleton organization and biogenesis |
| GO:0046907 | 1.80E-02 | Intracellular transport | ||
| GO:0007067 | 1.98E-02 | Mitosis | ||
| 41 | 6 | GO:0000075 | 1.63E-02 | Cell cycle checkpoint |
| GO:0007050 | 1.63E-02 | Cell cycle arrest | ||
| GO:0051242 | 3.55E-02 | Positive regulation of cellular process | ||
| GO:0000074 | 3.55E-02 | Regulation of cell cycle | ||
| GO:0042127 | 3.95E-02 | Regulation of cell proliferation | ||
Ng, number of genes in the module.