Table 5. Top 20 avian-specific gene families with known functions.
| Family ID | Turkey | Chicken | Zebra Finch | Non-Avian Species | Description |
| ENSFM00500000278106 | 5 | 5 | 2 | 0 | Cytidine deaminase |
| ENSFM00250000010664 | 1 | 3 | 1 | 0 | C type lectin |
| ENSFM00520000517850 | 1 | 3 | 10 | 0 | Class II histocompatibility antigen b l, beta chain fragment |
| ENSFM00250000011687 | 1 | 2 | 1 | 0 | Early response to neural induction ERNI |
| ENSFM00540000719139 | 1 | 1 | 1 | 0 | 16 kDa beta galactoside binding lectin C, 16 galectin (CG 16) |
| ENSFM00250000030665 | 1 | 1 | 1 | 0 | 2 receptor |
| ENSFM00500000306697 | 1 | 1 | 1 | 0 | 28 s ribosomal S6 mitochondrial S6mt MRP-S6 |
| ENSFM00540000721500 | 1 | 1 | 1 | 0 | Amyloid precursor |
| ENSFM00250000013480 | 1 | 1 | 1 | 0 | B6 BU |
| ENSFM00500000292985 | 1 | 1 | 1 | 0 | CD30 ligand |
| ENSFM00540000719360 | 1 | 1 | 2 | 0 | CD30 precursor |
| ENSFM00500000279114 | 1 | 1 | 2 | 0 | CD47 glycoprotein |
| ENSFM00540000720384 | 1 | 1 | 1 | 0 | CD5 precursor |
| ENSFM00540000719692 | 1 | 1 | 1 | 0 | CD80 |
| ENSFM00500000291092 | 1 | 1 | 1 | 0 | CD86 precursor |
| ENSFM00500000281340 | 1 | 1 | 1 | 0 | CENP-C |
| ENSFM00500000296154 | 1 | 1 | 1 | 0 | Centromere Q [CENP-Q] |
| ENSFM00540000721306 | 1 | 1 | 1 | 0 | Centromere U [CENP-U]; centromere p50 of 50 kDa CENP-50 MLF1 interacting protein |
| ENSFM00500000287565 | 1 | 1 | 1 | 0 | Cholecystokinin precursor CCK [contains cholecystokinin (CCK); CCK-8; CCK-7] |
| ENSFM00560000772828 | 1 | 1 | 1 | 0 | COMM domain-containing protein 6 |