Table 2. Risk of childhood malignancy in the offspring of women exposed to major radiodiagnostic testing in pregnancy compared to unexposed women.
Major Radiodiagnostic Test Exposure in Pregnancy | |||||
Exposed (n = 5,590) | Unexposed (n = 1,829,927) | HR (95% CI) | |||
n events (%) | Incidence rate per 10,000 person-years | n events (%) | Incidence rate per 10,000 person-years | Crude | Adjusteda |
4 (0.072) | 1.13 | 2,539 (0.14) | 1.56 | 0.69 (0.26–1.82) | 0.68 (0.25–1.80) |
Adjusted for maternal age at delivery (continuous in years), income quintile, urban status, and diagnosed maternal cancer in the index pregnancy and up to 6 mo thereafter, as well as infant sex, a chromosomal or congenital anomaly, and exposure to a major radiodiagnostic test exposure after birth.