Table 2.
Nine states of genoCNA
State | Copy number | Genotype |
---|---|---|
1 | 2 | AA, AB, BB |
2 | 2 | AA, (AA, AB), (BB, AB), BB |
3 | 0 | Null |
4 | 1 | (A, AA), (A, AB), (B, AB), (B, BB) |
5 | 3 | (AAA, AA), (AAB, AB), (ABB, AB), (BBB, BB) |
6 | 3 | (AAA, AA), (AAA, AB), (BBB,AB), (BBB, BB) |
7 | 4 | (AAAA, AA), (AABB, AB), (BBBB, BB) |
8 | 4 | (AAAA, AA), (AAAA, AB), (BBBB, AB), (BBBB, BB) |
9 | 4 | (AAAA, AA), (AAAB, AB), (ABBB, AB), (BBBB, BB) |
Genotype classes in parenthesis, such as (A, AB) are due to normal tissue contamination of genotype A from tumor tissue and genotype AB from normal tissue. Here we use underscore to indicate that the genotype is from normal tissue contamination.