Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Chemical structure of DC Bead and its proposed interaction with the active lactone (L) form of topotecan. The active lactone form is believed to bind to the DEBs and elute in this form. Once eluted topotecan can behave like free topotecan and converts to the more stable inactive carboxylate (C) form
