Table 1.
Patient Characteristics
| Total Group (n=225) |
Ischemic Group (n=59) |
Non- Ischemic Group (n=166) |
p-value | |
|---|---|---|---|---|
| Age (years) | 66 ±12 | 66 ±12 | 64 ± 11 | 0.24 |
| Gender and Ethnicity n, (%) | ||||
| Caucasian male | 121 (54) | 30 (48) | 91 (55) | 0.18 |
| Caucasian female | 44 (20) | 14 (22) | 30 (18) | 0.25 |
| African American male | 30 (13) | 8 (13) | 22 (13) | 1.0 |
| African American female | 30 (13) | 7 (11) | 23 (14) | 0.28 |
| BMI (kg/m2) | 29 ± 7 | 30 ± 6 | 29 ± 7 | 0.30 |
| Systolic BP (mmHg) | 144 ± 25 | 144 ± 21 | 146 ± 24 | 0.57 |
| Diastolic BP (mmHg) | 75 ± 17 | 75 ± 16 | 76 ± 17 | 0.69 |
| Presentation n, (%) | ||||
| Elective | 159 (71) | 44 (75) | 115 (69) | 0.19 |
| Unstable Angina | 50 (22) | 12 (20) | 38 (22) | 0.37 |
| Myocardial Infarction | 16 (7) | 3 (5) | 13 (8) | 0.22 |
|
Risk Factors/Past Medical History n, (%) |
||||
| Smoking | 124 (55) | 31 (52) | 93 (56) | 0.29 |
| Family history of CAD | 106 (48) | 31 (52) | 75 (47) | 0.25 |
| Hypertension | 167 (74) | 47 (79) | 118 (72) | 0.25 |
| Hyperlipidemia | 179 (80) | 52 (89) | 127 (77) | 0.02 |
| Diabetes | 87 (41) | 33 (56) | 60 (36) | 0.004 |
| Peripheral Vascular Disease | 19 (8) | 6 (10) | 13 (8) | 0.32 |
| Prior Myocardial Infarction | 75 (33) | 22 (37) | 53 (32) | 0.24 |
| Prior CABG | 54 (24) | 14 (23) | 40 (24) | 0.44 |
| Prior PTCA | 79 (35) | 27 (47) | 52 (31) | 0.01 |
| Prior CVA | 27 (12) | 5 (9) | 22 (13) | 0.21 |
| Baseline Medications n, (%) | ||||
| Beta blockers | 190 (84) | 49 (83) | 141 (85) | 0.36 |
| ACE inhibitors | 146 (65) | 38 (65) | 108 (65) | 1.0 |
| Calcium channel blockers | 59 (26) | 23 (39) | 36 (22) | 0.005 |
| Lipid lowering agents | 184 (82) | 50 (85) | 134 (81) | 0.45 |
| PPI | 76 (34) | 21 (36) | 55 (33) | 0.34 |
| Laboratory Data | ||||
| WBC (× 1000/mm3) | 7.8 ± 3.0 | 8.6 ± 3.8 | 7.5 ± 2.4 | 0.12 |
| Platelets (× 1000/mm3) | 231 ± 71 | 239 ± 69 | 228 ± 70 | 0.29 |
| Hemoglobin (g/dL) | 13.4 ± 2.0 | 13.0 ± 1.9 | 13.5 ± 2.1 | 0.10 |
| Hematocrit (%) | 39.9 ± 5.2 | 39.4 ± 5.0 | 40.1 ± 5.3 | 0.37 |
| Creatinine (g/dL) | 1.1 ± 0.5 | 1.1 ± 0.5 | 1.1 ± 0.6 | 1.0 |
ACE=angiotensin converting enzyme; BMI=body mass index; CABG=coronary artery bypass graft surgery; CAD=coronary artery disease; CVA=cerebrovascular accident; PTCA=percutaneous transluminal coronary angioplasty; WBC=white blood cells: PPI=proton pump inhibitors.