Table 1.
Follow-up status |
At least one follow-up visit |
|||||
---|---|---|---|---|---|---|
Characteristics | Followed (n=788) % |
Lost to follow-up (n=81) % |
P valuea |
One visit (n=39) % |
2+ visits (n=749) % |
P valuea |
Maternal | ||||||
Age at childbirth (y)b | 23.7 (7.1) | 21.5 (6.0) | 0.01 | 23.7 (7.5) | 23.7 (7.0) | 0.45 |
Education (y) | 0.02 | 0.04 | ||||
None | 4.2 | 6.2 | 5.1 | 4.1 | ||
1 - 6 | 30.7 | 46.9 | 25.6 | 31.0 | ||
7 - 9 | 31.0 | 25.9 | 15.4 | 31.8 | ||
10 - 12 | 24.0 | 13.6 | 43.6 | 23.0 | ||
>12 | 10.2 | 7.4 | 10.3 | 10.1 | ||
Pre-pregnancy BMI (kg/m2)c |
0.90 | 0.99 | ||||
≤18.5 | 7.2 | 4.9 | 7.7 | 7.2 | ||
18.6 - <25.0 | 57.5 | 46.9 | 56.4 | 57.5 | ||
25.0 - <30.0 | 25.3 | 16.0 | 25.6 | 25.2 | ||
≥30 | 10.0 | 6.2 | 10.3 | 10.0 | ||
Smoked during pregnancy |
1.1 | 1.2 | 0.63 | 0.0 | 1.2 | |
Drank alcohol during pregnancyc |
2.9 | 4.9 | 0.24 | 7.7 | 2.7 | 0.10 |
First prenatal care visit |
<0.01 | 0.51 | ||||
None | 36.0 | 55.6 | 43.6 | 35.6 | ||
First trimester | 42.6 | 24.7 | 41.0 | 42.7 | ||
After first trimester |
21.3 | 19.8 | 15.4 | 21.6 | ||
Parityde | 0.28 | 0.07 | ||||
1 | 41.4 | 46.9 | 56.4 | 40.6 | ||
2 | 34.9 | 37.0 | 33.3 | 35.0 | ||
3+ | 23.7 | 16.0 | 10.3 | 24.4 | ||
Age at menarche (y)bc |
13.0 (2.0) | 13.0 (2.0) | 0.40 | 13.0 (2.0) | 13.0 (2.0) | 0.88 |
Height (cm)b | 152.5 (7.7) | 151.4 (8.1) | 0.04 | 149.9 (7.5) | 152.6 (7.8) | 0.05 |
Serum p,p’-DDE (μg/g)bf |
2.7 (4.3) | 1.7 (3.8) | 0.01 | 1.6 (2.4) | 2.7 (4.6) | <0.01 |
Serum p,p’-DDT (μg/g)bf |
0.3 (0.6) | 0.2 (0.5) | <0.01 | 0.2 (0.2) | 0.3 (0.7) | <0.01 |
Worked outside homee |
31.5 | 35.8 | 0.43 | 33.3 | 31.4 | 0.80 |
Hospital of recruitment |
<0.01 | 0.68 | ||||
Social Security | 49.4 | 28.4 | 46.2 | 49.5 | ||
Ministry of Health | 50.6 | 71.6 | 53.8 | 50.5 | ||
Residence areae | 0.81 | 0.29 | ||||
Urban | 59.4 | 58.0 | 51.3 | 59.8 | ||
Rural | 40.6 | 42.0 | 48.7 | 40.2 | ||
Poverty indexceg | 0.07 | 0.86 | ||||
Poorest | 70.7 | 66.7 | 66.7 | 70.9 | ||
Less poor | 19.0 | 11.1 | 20.5 | 19.0 | ||
Not poor | 10.2 | 2.5 | 10.3 | 10.1 | ||
Home ownerc | 17.9 | 35.9 | 0.18 | |||
Child | ||||||
Gestational age (wk)b | 40.0 (1.0) | 39.0 (1.0) | 0.13 | 39.7 (2.0) | 40.0 (1.0) | 0.09 |
Birth season | 0.51 | 0.38 | ||||
Winter | 20.1 | 14.8 | 28.2 | 19.6 | ||
Spring | 28.8 | 35.8 | 33.3 | 28.6 | ||
Summer | 28.0 | 27.2 | 23.1 | 28.3 | ||
Autumn | 23.1 | 22.2 | 15.4 | 23.5 | ||
Age at introduction of formula or cow’s milk (mo)bgh |
6.0 (8.5) | 3.0 (7.5) | 0.06 | |||
Breastfeed everh | 97.4 | 98.7 | 0.43 | |||
Ever exclusively breastfeedh |
89.7 | 83.3 | 0.29 | |||
Duration of any breastfeeding (mo)bh |
10.0 (9.8) | 11.0 (12.9) | 0.08 | |||
Duration of exclusive breastfeeding (mo)bh |
0.1 (2.0) | 0.1 (1.0) | 0.86 | |||
Age at introduction of grains and cereal (mo)bh |
7.0 (6.0) | 6.0 (3.0) | 0.02 | |||
Number of older siblings |
0.22 | <0.01 | ||||
0 | 43.0 | 53.1 | 59.0 | 42.2 | ||
1 | 36.3 | 30.9 | 38.5 | 36.2 | ||
2+ | 20.7 | 16.0 | 2.6 | 21.6 | ||
Had a younger sibling during follow-uph |
7.7 | 10.0 | 0.11 |
Abbreviations: BMI, body mass index; DDE, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene; DDT, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane
Comparing subjects by follow-up status (followed vs. lost to follow-up) and those with at least one visit (one vs. 2+ visits) using Pearson’s chi-squared or Fisher’s exact tests for categorical and Kruskal-Wallis equality-of-populations rank test for continuous variables. All tests were two-sided
Median (interquartile range)
Variables with missing data: ≤ 2.5%, except for mother’s pre-pregnancy BMI (25.9%), age at menarche (49.4%), and poverty index (19.8%) in the lost to follow-up group
Parity of one at recruitment reflects the birth of the study child
Time-varying variables, information for those with at least one follow-up visit reflects their status at first visit
Determined from maternal serum samples drawn at delivery of the study child
Defined using Mexican national standards based on monthly per capita income: Urban (Poorest, ≤672 pesos; Less poor, >672 to ≤1,367; Not poor, >1,367) and Rural (Poorest, ≤ 495; Less poor, >495 to ≤946; Not poor, >946) (Cupul-Uicab et al., 2008)
The information was asked only in the follow-up study