Table 3.
Unadjusted β coefficientsb |
Adjusted β coefficientsc |
|||||||
---|---|---|---|---|---|---|---|---|
Main effectd | 95% CI | Interactione | 95% CI | Main effectd | 95% CI | Interactione | 95% CI | |
Interceptfg | −0.031 | −0.100, 0.039 | 0.012 | 0.007, 0.017 | 0.555 | 0.344, 0.766 | 0.014 | −0.003, 0.030 |
p,p’-DDE (μg/g)h | ||||||||
≤3.00 | Reference | Reference | ||||||
3.01-6.00 | −0.124 | −0.298, 0.049 | 0.018 | 0.005, 0.030 | −0.121 | −0.284, 0.042 | 0.019 | 0.006, 0.032 |
6.01-9.00 | −0.054 | −0.306, 0.199 | −0.008 | −0.026, 0.010 | −0.030 | −0.267, 0.207 | −0.005 | −0.023, 0.013 |
>9.00 | −0.027 | −0.235, 0.181 | 0.004 | −0.011, 0.019 | 0.069 | −0.131, 0.268 | 0.010 | −0.006, 0.025 |
Smoked during pregnancyi |
0.554 | −0.143, 1.250 | −0.003 | −0.055, 0.049 | 0.485 | −0.165, 1.135 | −0.006 | −0.057, 0.045 |
Hospital of recruitmenti | ||||||||
Ministry of Health |
−0.462 | −0.597, −0.326 | −0.008 | −0.018, 0.002 | −0.280 | −0.421, −0.139 | −0.004 | −0.014, 0.007 |
Rural residence at recruitmenti |
−0.198 | −0.341, −0.055 | −0.012 | −0.023, −0.002 | −0.052 | −0.194, 0.090 | −0.012 | −0.023, −0.001 |
Gestational age (wk)g |
0.059 | −0.010, 0.129 | 0.004 | −0.001, 0.009 | 0.041 | −0.024, 0.105 | 0.003 | −0.002, 0.008 |
Maternal education (years) | ||||||||
None | −1.018 | −1.407, −0.630 | −0.029 | −0.057, −0.002 | −0.507 | −0.899, −0.115 | −0.015 | −0.044, 0.014 |
1 - 6 | −0.801 | −1.041, −0.562 | −0.008 | −0.026, 0.010 | −0.461 | −0.708, −0.215 | 0.001 | −0.018, 0.020 |
7 - 9 | −0.683 | −0.921, −0.444 | 0.001 | −0.017, 0.019 | −0.471 | −0.706, −0.236 | 0.006 | −0.012, 0.024 |
10 - 12 | −0.404 | −0.653, −0.155 | −0.002 | −0.021, 0.016 | −0.330 | −0.568, −0.093 | 0.000 | −0.018, 0.018 |
> 12 | Reference | Reference | ||||||
Maternal heightg |
0.051 | 0.040, 0.063 | 0.001 | 0.000, 0.002 | 0.040 | 0.029, 0.052 | 0.001 | 0.000, 0.002 |
Abbreviations: CI, confidence interval; DDE, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene; SDS, standard deviation scores
SDS, standard deviation scores internally derived at each age point as: measurement - population mean/population standard deviation. Height was missing for one observation
Unadjusted coefficients were obtained from models that also included a term for child’s age at measurements and subject-specific random intercepts and random slopes for age
Adjusted for all variables listed in the table (variables selected a priori)
Main effect term or initial status, represents the average difference in height SDS at 15.7 months of age (median age at first measurement) in a given category or value of a covariate
Interaction with child’s age at measurement (months), represents the average monthly rate of change (growth) in height SDS in a given category or value of a covariate
The intercept for the main effect term in the adjusted model represents the average height SDS at the median age at the first measurement (15.7 months) for children in the lowest exposure group (DDE, ≤3.00 μg/g lipids) with reference values for the other covariates included in the model; and the interaction term for the intercept represents the average monthly rate of change in height SDS in the lowest exposure group (DDE, ≤3.00 μg/g lipids) with reference values for the other covariates included in the model
Variables were median-centered as follow: age at measurements, 15.7 months; gestational age, 40 wk; maternal height, 152.5 cm
Determined from maternal serum samples drawn at delivery of the study child
Reference groups were: smoked during pregnancy, No; hospital of recruitment, Social Security; residence at recruitment, Urban