TABLE II. Expression of Intracellular IL-10 and TGF-β1 by CD14+HLA-DRlow/− Cells and CD14+ HLA-DR+ Cells From Treated Prostate Cancer Patients (tPCa) and Age-Matched Controls.
Subject | HLA-DRlow/− cells, percent of CD14+ cells | IL-10 expressing cells | TGF-β1 expressing cells | ||||
---|---|---|---|---|---|---|---|
HLA-DRlow/− cells | HLA-DR+ cells | P-valuea | HLA-DRlow/− cells | HLA-DR+ cells | P-valuea | ||
b P27 | 14.0 | 90.4c | 73.4 | 43.6 | 33.6 | ||
P28 | 20.8 | 40.6 | 13.5 | 25.9 | 18.6 | ||
P29 | 24.3 | 89.2 | 69.0 | 0.0244 | 44.3 | 41.2 | 0.5405 |
A18 | 1.7 | 70.0 | 13.8 | 8.8 | 15.7 | ||
A19 | 5.0 | 40.4 | 26.4 | 47.2 | 50.2 |
Two-sided values calculated by paired Student's t-test for paired samples.
P denotes tPCa patients, A the age-matched controls (both indicated by ** in Supplementary Table I).
Percentage of CD14+HLA-DRlow/− cells and CD14+HLA-DRhigh/+ cells, respectively, expressing IL-10 or TGF-β1.