TABLE 1.
Demographic and cognitive measures of subjects with and without restless legs syndrome
| With RLS: mean (SD), N | Without RLS: mean (SD), N | Δ | 95% CI | P* | |
|---|---|---|---|---|---|
| Age (yr) | 76.8 (9.2), 26 | 78.1 (9.0), 208 | −1.4 | −5.0 to 2.3 | 0.46 |
| Duration of education (yr) | 15.3 (2.8), 26 | 15.1 (2.6), 208 | 0.2 | −0.9 to 1.3 | 0.71 |
| Folstein MMSE | 28.2 (1.7), 25 | 28.7 (1.6), 204 | −0.5 | −1.2 to 0.2 | 0.15 |
| AVLT total learning | 47.7 (9.1), 26 | 44.7 (11.3), 205 | 3.0 | −1.6 to 7.5 | 0.19 |
| AVLT Trial 1 | 5.7 (1.7), 26 | 5.5 (2.1), 205 | 0.2 | −0.6 to 1.0 | 0.64 |
| AVLT Trial 2 | 8.5 (1.9), 26 | 8.2 (2.6), 205 | 0.2 | −0.8 to 1.3 | 0.67 |
| AVLT Trial 3 | 10.0 (2.5), 26 | 9.6 (2.7), 205 | 0.4 | −0.7 to 1.5 | 0.49 |
| AVLT Trial 4 | 11.4 (2.2), 26 | 10.3 (2.7), 205 | 1.1 | 0.01 to 2.2 | 0.048 |
| AVLT Trial 5 | 12.1 (2.1), 26 | 11.0 (2.7), 205 | 1.1 | 0.01 to 2.2 | 0.047 |
| AVLT intrusions (1–5) | 0.6 (1.2), 25 | 1.5 (2.3), 200 | −0.9 | −1.8 to 0.0 | 0.06 |
| AVLT STM (A6) | 9.6 (3.4), 26 | 9.0 (3.3), 205 | 0.5 | −0.8 to 1.9 | 0.43 |
| AVLT intrusions (STM) | 0.36 (0.70), 25 | 0.50 (0.96), 200 | −0.14 | −0.52 to 0.25 | 0.50 |
| AVLT LTM (A7) | 9.0 (3.5), 26 | 8.9 (3.7), 205 | 0.1 | −1.4 to 1.6 | 0.88 |
| AVLT LT % recall | 73 (24), 26 | 79 (26), 205 | −6 | −17 to 4 | 0.25 |
| AVLT List B | 5.2 (2.0), 26 | 4.8 (2.0), 204 | 0.4 | −0.4 to 1.2 | 0.33 |
| AVLT recognition TP | 13.5 (1.7), 25 | 13.2 (2.3), 199 | 0.3 | −0.7 to 1.2 | 0.56 |
| AVLT recognition FP | 0.20 (0.41), 25 | 0.64 (1.25), 199 | −0.44 | −0.94 to 0.05 | 0.08 |
| WAIS digit span - forward | 8.6 (1.5), 24 | 9.6 (2.0), 188 | −1.0 | −1.8 to −0.2 | 0.02 |
| WAIS digit span - backward | 6.2 (1.8), 24 | 6.4 (2.0), 187 | −0.2 | −1.1 to 0.6 | 0.60 |
| WAIS digit span - total | 14.8 (2.6), 24 | 16.0 (3.3), 187 | −1.2 | −2.6 to 0.2 | 0.09 |
| WAIS digit span - backward span | 4.6 (1.2), 23 | 4.7 (1.2), 182 | −0.1 | −0.6 to 0.4 | 0.74 |
| WAIS digit span - forward span | 5.7 (0.9), 23 | 6.3 (1.2), 183 | −0.6 | −1.1 to −0.1 | 0.03 |
| Clock drawing | 9.0 (1.6), 25 | 9.2 (1.1), 204 | −0.3 | −0.8 to 0.2 | 0.26 |
| STROOP word (#) | 87 (15), 24 | 89 (16), 199 | −2 | −8.9 to 5.0 | 0.58 |
| STROOP color (#) | 63 (12), 23 | 63 (12), 196 | 0 | −5 to 5 | 0.98 |
| STROOP word/color (#) | 32.6 (7.0), 23 | 33.0 (10.1), 19 | −0.4 | −4.6 to 3.9 | 0.86 |
| STROOP uncorrected W/C errors | 0.4 (1.1), 22 | 0.4 (1.0), 191 | 0.1 | −0.4 to 0.5 | 0.72 |
| STROOP interference | −4.0 (5.4), 23 | −4.0 (7.2), 195 | 0.0 | −3.1 to 3.0 | 0.99 |
| TRAILS A/B - time (3 min limit) | 37 (16), 24 | 38 (22), 203 | −1 | −10 to 78 | 0.79 |
| TRAILS A/B - A errors | 0.13 (0.34), 24 | 0.12 (0.42), 203 | 0.01 | −0.17 to 0.18 | 0.94 |
| TRAILS A/B - B (5 min limit) | 101 (43), 24 | 102 (53), 200 | −1 | −24 to 21 | 0.90 |
| TRAILS A/B - B errors | 0.46 (0.72), 24 | 0.57 (1.11), 201 | −0.11 | −0.57 to 0.35 | 0.64 |
| COWA (CFL) total | 38 (16), 26 | 38 (12), 205 | 1 | −4 to 6 | 0.79 |
| COWA (CFL) perseverations | 2.8 (2.9), 25 | 2.8 (2.7), 200 | 0.0 | −1.2 to 1.1 | 0.97 |
| COWA (CFL) intrusions | 0.08 (0.28), 25 | 0.29 (0.64), 200 | −0.21 | −0.46 to 0.05 | 0.12 |
| Animal fluency | 16.7 (5.2), 26 | 16.8 (5.0), 204 | −0.1 | −2.2 to 2.0 | 0.91 |
| Animal fluency perseverations | 1.0 (1.4), 25 | 1.0 (1.3), 199 | 0.0 | −0.5 to 0.5 | 1.00 |
| Judgment of line orientation | 23.6 (3.9), 23 | 23.7 (4.3), 191 | −0.1 | −2.0 to 1.7 | 0.89 |
| GDS | 3.7 (3.2), 26 | 3.4 (3.7), 206 | 0.4 | −1.1 to 1.8 | 0.63 |
*
Two sample t test.