Table 2.

Summary of Topical Antimicrobial Therapy Agents used for Burns Covered in this Review

Agent Class	Specific Agent	Application	Ref
Skin Substitutes	Duoderm	Clinical 2nd degree burns	[25]
	Trans-Cyte	Clinical 2nd degree burns	[26]
	Omniderm	Clinical 2nd degree burns	[27]
	Suprathel	Clinical 2nd degree burns	[28]
	Epigard	Clinical 2nd degree burns	[29]
	SYSpur-derm	Clinical 2nd degree burns	[30]
	Biobrane	Clinical 2nd degree burns	[31]
	Xenoderm	Clinical 2nd degree burns	[32]
Topical antibiotics	Mafenide acetate	Clinical 2nd/3rd degree burns	[33]
	Bacitracin	Clinical 2nd/3rd degree burns	[34]
	Mupirocin	Clinical 2nd/3rd degree burns	[35]
	Neosporin	Clinical 2nd/3rd degree burns	[36]
	Polymyxin B	Clinical 2nd/3rd degree burns	[37]
	Nitrofurazone	Clinical 2nd/3rd degree burns	[38]
	Nystatin	Clinical 2nd/3rd degree burns, fungal infections	[35]
Silver	Silver nitrate	Clinical 2nd/3rd degree burns	[39]
	Silver sulfadiazine	Clinical 2nd/3rd degree burns	[40]
	Silver foams (Contreet, Allevyn)	Clinical 2nd/3rd degree burns	[41]
	Flammacerium	Clinical 2nd/3rd degree burns	[42]
	Acticoat 7	Clinical 2nd/3rd degree burns	[43]
	Aquacel-Ag	Clinical 2nd/3rd degree burns	[44]
	Silvercel	Clinical 2nd/3rd degree burns	[45]
	Silver amniotic membrane (	Clinical 2nd/3rd degree burns	[46]
Iodine	Povidone-iodine	Clinical 2nd/3rd degree burns	[47]
	Cadexomer iodine (Iodosorb)	Clinical chronic wounds	[48]
	Liposomal iodine, Repithel	Clinical 2nddegree burns	[49]
	Iocide	Oral infections	[50]
Photodynamic therapy	TBO	Mouse wound infections	[51]
	PEI-ce6	Mouse burn infections (A. baumannii)	[52]
	XF73	In vitro, ex vivo skin infection	[53]
	BB6	In vitro, mouse wound infection	[54]
	Sylsens B	Mouse burn infection S. aureus	[55]
	DP/hemin	Guinea pig burn infections S. aureus	[56]
	Cat PC	In vitro, veterinary infections	[57]
	EtNBSe	In vitro	[58]
Chitosan	hydrogel	Clinical 2nd degree burns	[59]
	film	2nd degree burns in rabbits	[60]
	bandage	Mouse burn infections (Psuedomonas, Proteus)	[61]
Antimicrobial peptide	Defensins	In vitro	[62]
	Demegel	Pseudomonas infected rat burns	[63]
	Histone H1.2	Pseudomonas infected rat burns	[64]
	Cecropin B	Pseudomonas infected mouse wounds	[65]
	rBPI	Clinical trial 2nd degree burns	[66]
	Ceragenins	In vitro	[67]
Miscellaneous	Chlorhexidine (LM Miller)	Infected rat burns, clinical trial	[68, 69]
	Superoxidized water	In vitro	[70]
	BCTP nanoemulsion	In vitro	[71]
	FPQC	Mice burns, Pseudomonas	[72]
	Acidified nitrite	In vitro	[73]
	Phage therapy	Mice burns, Pseudomonas	[74]
	p38MAPK inhibitor	Rat burns, Pseudomonas	[75]
	Probiotics, Lactobacillus	Clinical trial, 2nd, 3rd degree	[76]
	Honey	Clinical trial, 2nd degree	[77]
	Essential oils	In vitro	[78]
	MEBO	Clinical trial, 2nd degree	[79]
	Papaya	Clinical trial, 2nd, 3rd degree	[80]