Table S4.

Across-paralog comparison of the exon patterns for Cpeb2. The numbers represent the lengths of exons in a sequential order. The locations and size of exons were determined by aligning the cDNA sequence to the genomic sequence. For simplicity, only one RefSeq sequence is used for each organism. The pattern in C. elegans is not consistent with those in the vertebrates. However the patterns among the vertebrates are highly conserved. The asterisks represent the variable regions of ±90-nt and ±24-nt discussed in the text, which would subsequently lead to 30-aa and 8-aa deletion or insertion. The pound sign indicates a newly updated isoform in which the use of an alternative exon leads to an extralong protein.

C. elegans								47	337	174	236	776	196	NM_062835.2
cow			295		91	51	24	171	90	119	115	182	3994	XM_001787297.1
horse			289		91	51	24	171	90	119	115	182	3992	XM_001498900.2
human (new)		1662	282		91	51		171	90	119	115	182	4001	NM_182646.2
human		438	282		91	51		171	90	119	115	182	3998	NM_182646.1
mouse (new)		1626#	282	90	91	51		171	90	119	115	182	4006	NM_175937.3
mouse	59	200	282	90	91	51		171	90	119	115	182	472	NM_175937.2
rat		203	265	90	91	51		171	90	140	115	182	4003	NM_001108361.1
zebrafish			224		91	51		174	90	119	115	182	307	NM_001177457.1
				*			*