Table 1. IC50 values of Phyllanthus extracts and standard anticancer drugs on both human cancer and normal cell lines.
| IC50± SEM (μg/ml) | |||||
| Skin cells | Prostate cells | ||||
| Phyllanthus species | Extracts | Cancer (MeWo) | Normal (CCD-1127Sk) | Cancer (PC-3) | Normal (RWPE-1) |
| P.amarus | Aqueous | 193.3±1.3 | >500 | 178.3±2.8 | >500 |
| Methanol | 133.3±2.9 | >500 | 84.3±1.1 | >500 | |
| P.niruri | Aqueous | 260.0±2.4 | >500 | 155.0±1.2 | >500 |
| Methanol | 153.3±2.6 | >500 | 117.7±2.1 | >500 | |
| P.urinaria | Aqueous | 193.3±1.1 | >500 | 155.7±2.1 | >500 |
| Methanol | 56.21±3.2 | >500 | 54.2±2.1 | >500 | |
| P.watsonii | Aqueous | 160.0±3.2 | >500 | 156.7±2.4 | >500 |
| Methanol | 100.7±2.0 | >500 | 100.5±1.2 | >500 | |
| 5′-Fluorouracil | 2.3±0.5 | 0.8±0.5 | 1.0 ±0.3 | 1.0±0.5 | |
| Doxorubicin | 2.5±0.5 | 1.0±0.2 | 2.5 ±0.5 | 1.0±0.1 | |