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Whole-cell current-voltage relations for wt-Kir1.1b, with either 100 mM extracellular K (black) or 100 mM extracellular Rb (green). Currents were measured on the same oocyte in response to applied clamp voltages between -200 mV and +200 mV. Oocyte internal [K] was approximately 100 mM and acetate buffers were used to clamp the oocyte internal pH at 7.8. Fitted lines indicate either K (black) or Rb (green) inward conductances. Inset shows raw data.
