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. Author manuscript; available in PMC: 2011 May 2.
Published in final edited form as: Channels (Austin). 2010 MAY-JUN;4(3):203–214. doi: 10.4161/chan.4.3.11982

Figure 12.

Figure 12

Voltage dependence of open probability (Po) for the single-channel Rb current of R128Y in Figure 9, compared to wt-Kir1.1 Rb permeation (dashed line). Curve is the best fit to the Boltzman Eq: Po = Bottom + (Top - Bottom)/(1 + exp((V50 - V)/slope)), where V50 = -117 mV and slope = 30, for R128Y and V50 = -181 mV and slope = 41, for wild-type.