Figure 12.
Voltage dependence of open probability (Po) for the single-channel Rb current of R128Y in Figure 9, compared to wt-Kir1.1 Rb permeation (dashed line). Curve is the best fit to the Boltzman Eq: Po = Bottom + (Top - Bottom)/(1 + exp((V50 - V)/slope)), where V50 = -117 mV and slope = 30, for R128Y and V50 = -181 mV and slope = 41, for wild-type.