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Semi-log plot of R128Y reversal potentials associated with progressive replacement of external Na by: K (open squares), Rb (closed circles), Tl (open triangles) or NH4 (open circles), at constant ionic strength. Permeability ratios were fit by Eqs 1–3 (Methods) and given in Table 2. Inset shows an example of R128Y inward and outward currents during isosmolar replacement of external Na by Rb.
