Table 2.

Effects of KMUP-1, sildenafil and zaprinast on blood oxygenation during hypoxia induced by infusion of U46619 in rats

	Control	U46619	KMUP-1 + U46619	Sildenafil + U46619	Zaprinast + U46619
PO2	103.2 ± 10.4	89.3 ± 3.1#	100.1 ± 2.2*	100.6 ± 3.0*	98.5 ± 3.1*

Data in the table are means ± s.e., n= 6. U46619 was infused at 2.5 µg·kg⁻¹·min⁻¹, i.v. for 30 min and blood samples taken from the femoral artery at the end of the infusion.

^*P < 0.05 versus U46619,

^#P < 0.05 versus control values.