Table 1.

Mean seizure frequency per day of responders and non-responders

	Selection phase				Second treatment phase
	Pre-drug		Phenobarbital		Vehicle		Celecoxib		Phenobarbital
	Mean±SEM	n	Mean±SEM	n	Mean±SEM	n	Mean±SEM	n	Mean±SEM	n
Data of all animals included in the respective experimental phase
Responder	0.86 ± 0.30	5	0.14 ± 0.10	5	1.40 ± 0.91	5	0.63 ± 0.40	5	0.50 ± 0.34	4
Non-responder	3.14 ± 1.68	7	2.63 ± 1.75	7	6.31 ± 4.65	5	6.17 ± 2.79	5	2.20 ± 2.20	4
Data of those animals that completed all experimental phases
Responder	1.03 ± 0.32	4	0.17 ± 0.13	4	1.75 ± 1.09	4	0.79 ± 0.47	4	0.50 ± 034	4
Non-responder	4.80 ± 2.77	4	4.01 ± 3.04	4	7.68 ± 5.74	4	6.46 ± 3.47	4	2.20 ± 2.20	4

The Table gives the average seizure frequency per day during the different treatment phases of the selection phase (pre-drug: 16 days, phenobarbital: 16 days) and second treatment phase (vehicle: 7 days; celecoxib: 6 days; phenobarbital: 16 days) for both groups of rats, designated responders and non-responders according to the first phenobarbital treatment phase. Please note that four animals died during different experimental phases, so that the number of animals included changed. To allow a better comparison, data of the animals that completed all experimental phases are given separately.