Table 2.
Effect of meat-based diets on aberrant crypt foci and mucin-depleted foci in the colon of rats 107 d after the injection of dimethylhydrazinea
Dietsb | Heme intake | Aberrant Crypt Foci |
Mucin Depleted Foci |
||||||
---|---|---|---|---|---|---|---|---|---|
ACF/colon | Crypts/ACF | MDF/colon | Crypts/MDF | ||||||
μmol/day | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
Control | 0 | 105 | 24 | 2.3 | 0.2 | 3.5 | 2.0 | 4.6 | 1.7 |
Ham | 0.45 | 119c | 16 | 2.1 | 0.1 | 8.5c | 2.2 | 4.3 | 1.2 |
Values are means and SD, N = 10 rats/dietary group
Diets were based on a low calcium formula, as shown in Table 1.
Significantly different from control group by 2-way ANOVA (ACF, P<0.05) and by Welsh’s test (MDF, P<0.0001)