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Administration of COG1410 reduced tissue loss following FPI. Analysis of the percent reduction in injured cortical volume compared to contralateral cortex is shown. Plotted are the mean (+SEM) percent reductions in cortical volume for each group. COG1410 treatment (1.0 mg/kg) significantly reduced the amount of injury-induced tissue reduction compared to vehicle treatment following unilateral FPI (* = p<0.05).
