Table 2.
Comparison between IHC or FISH results and histopathological parameters
| Characteristics | FISH analysis | IHC analysis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CyclinD1 | h-prune | p53 | pERK1-2 | survivin | ||||||
| positive cases | % | positive cases | % | positive cases | % | positive cases | % | positive cases | % | |
| Total patients (N = 53) | 12 | 23 | 8 | 15 | 13 | 25 | 5 | 9 | 21 | 40 |
| Estrogen receptor (ER) | ||||||||||
| negative (N = 20) | 2 | 10 | 1 | 5 | 4 | 20 | 2 | 10 | 9 | 45 |
| positive (N = 24) | 7 | 29 | 5 | 11 | 5 | 21 | 2 | 8 | 7 | 29 |
| Progesterone receptor (PR) | ||||||||||
| negative (N = 28) | 5 | 18 | 2 | 7 | 5 | 18 | 2 | 7 | 13 | 46 |
| positive (N = 16) | 4 | 25 | 4 | 25 | 4 | 25 | 2 | 12 | 3 | 19 |
| Ki67 | ||||||||||
| negative (N = 26) | 4 | 15 | 3 | 12 | 4 | 15 | 4 | 15 | 11 | 42 |
| positive (N = 16) | 4 | 25 | 2 | 12 | 5 | 31 | 0 | 0 | 5 | 31 |
| HER2 | ||||||||||
| 0-1 (N = 16) | 5 | 31 | 3 | 19 | 2 | 12 | 2 | 12 | 9 | 56 |
| 2-3 (N = 37) | 7 | 19 | 5 | 14 | 11 | 30 | 3 | 8 | 12 | 32 |