Table 3.

Comparison between histopathological or molecular parameters and response to therapy

A
Outcome	ER			PR			Ki67			HER2
	positives	%	P	positives	%	P	positives	%	P	positives	%	P
Clinical response			0.132			0.640			0.047			0.022
Complete response	3/7	43		3/7	43		5/7	71		8/8	100
Partial response	16/29	55		11/29	38		9/27	33		27/37	73
< Partial response	5/8	62		2/8	25		2/8	25		2/8	25
Pathological response			0.469			0.235			0.042			0.095
pCR	4/7	57		3/7	43		5/7	71		7/8	87
<pCR	20/37	54		13/37	35		11/35	31		30/45	67
B
Outcome	cyclinD1			h-prune			pERK1-2			p53			survivin
	positives	%	P	positives	%	P	positives	%	P	positives	%	P
Clinical response			0.457			0.824			0.032			0.391			0.089
Complete response	1/8	12		1/8	12		0/8	0		1/8	12		1/8	12
Partial response	8/37	22		5/37	14		3/37	8		10/37	27		15/37	41
< Partial response	3/8	37		2/8	25		2/8	25		2/8	25		5/8	62
Pathological response			0.660			0.822			0.007			0.972			0.234
pCR	2/8	25		1/8	12		0/8	0		2/8	25		3/8	37
<pCR	10/45	22		7/45	16		5/45	11		11/45	24		18/45	40

pCR, pathological complete response