Table 1.
Characteristics of literatures included in the meta-analysis
| References | Year | Country | Ethnicity | Genotype distribution | HWE (controls) | MAF | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| case | control | ||||||||||
| GG | GA | AA | GG | GA | AA | ||||||
| Angele [30] | 2003 | France | European | 192 | 56 | 6 | 240 | 65 | 7 | Yes | 0.13 |
| Buchholz [31] | 2004 | USA | Mixed | 39 | 17 | 2 | 394 | 119 | 15 | Yes | 0.14 |
| Dork [32] | 2001 | Germany | European | 753 | 235 | 12 | 422 | 74 | 4 | Yes | 0.08 |
| Gonzalez-Hormazabal [29] | 2008 | Chile | South American | 100 | 26 | 0 | 174 | 26 | 0 | Yes | 0.07 |
| Heikkinen [33] | 2005 | Finland | European | 68 | 44 | 9 | 174 | 109 | 23 | Yes | 0.25 |
| Renwick [34] | 2006 | UK | European | 339 | 98 | 6 | 371 | 131 | 19 | Yes | 0.16 |
| Schrauder [35] | 2008 | Germany | European | 406 | 99 | 9 | 369 | 129 | 13 | Yes | 0.15 |
| Tapia [27] | 2008 | Chile | South American | 74 | 19 | 1 | 183 | 15 | 2 | No | 0.05 |
| Tommiska [36] | 2006 | Finland | European | 954 | 561 | 66 | 404 | 260 | 38 | Yes | 0.24 |
HWE, Hardy-Weinberg equilibrium
MAF, minor allele frequency