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. 2010 Aug 17;11:100. doi: 10.1186/1471-2202-11-100

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Copyright ©2010 Nakamura et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fos staining in prelimbic areas of the PFC. A: An untreated control showed Fos positive cells in the prelimbic area. B: LFS significantly decreased Fos expression in the ipsilateral prelimbic area. C: An untreated control showed Fos positive cells in the cingulate area. Scale lines represent 50 μm. D: Numbers of Fos-expressing cells in the ipsilateral and contralateral prelimbic areas before and after LFS. Fos positive cells were decreased in the prelimbic area. CN: control, LFS: low frequency stimulation *** P < 0.001. E: Numbers of Fos-expressing cells in the ipsilateral and contralateral cingulate areas before and after HFS.