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. 2010 Jul 21;21(9):1093–1103. doi: 10.1089/hum.2010.040

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Copyright 2010, Mary Ann Liebert, Inc.

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FIG. 2. — Coinfusion of AAV2-hASM-HA and gadoteridol (Gd) into the brainstem (open circles) and thalamus (solid circles). Shown are the results of single delivery of various amounts of infusate into the brainstem (open circles, n = 6; mean V_i:V_d ratio, 3.3 ± 0.17) and thalamus (solid circles, n = 10; mean V_i:V_d ratio, 3.86 ± 0.25). There is a linear relationship between V_d and V_i (overall, n = 16, R² = 0.93), with higher V_i delivered to the brainstem region as compared with the thalamus. No significant difference was found between ratios in these two regions (p > 0.05).