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. 2010 Sep 9;6(9):e1000925. doi: 10.1371/journal.pcbi.1000925

Figure 1. Workflow for the pipeline used to normalize and analyze Connectivity Map microarray experiments.

Figure 1

The reliability of drug-induced gene expression profile similarity scores (DIPS scores) were evaluated using independent drug features as benchmark. Using the processed data, differential regulation of drug-induced drug targets was investigated.