Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Sep 9;6(9):e1000928. doi: 10.1371/journal.pcbi.1000928

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Pandey et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

One feature is overlaid with another feature to generate an overlay feature. Each feature is treated as an undirected network with the genes as the nodes, and the value of the feature for a gene pair becomes the weight of the edge connecting them. Given two weighted networks and , corresponding to two features respectively, the value of the overlay feature for two nodes A and B, is the strongest (max of product of weights of the two edges) transitive link, i.e., , where and or vice versa.

Inline graphic — One feature is overlaid with another feature to generate an overlay feature. Each feature is treated as an undirected network with the genes as the nodes, and the value of the feature for a gene pair becomes the weight of the edge connecting them. Given two weighted networks and , corresponding to two features respectively, the value of the overlay feature for two nodes A and B, is the strongest (max of product of weights of the two edges) transitive link, i.e., , where and or vice versa.