Figure 1.
Secondary structure content of calculated ensembles for (a) I-29–164, (b) spinophilin417–494 and (c) DARPP-321–118. Lines represent the α-helix populations (green), populations in the broad α (blue), left-β (red) and right-β (purple) regions of the Ramachandran diagram. All values are plotted with a three-residue smoothing. Secondary structures observed in the bound-state crystal structures of I-2 and spinophilin are shown above the plots with α-helices in green, βstrands in red and other observed regions in blue.