Table 1.
Participant characteristics for biomarker groups.
| MCBP | Aβ42 | Tau | Ptau181 | |||||
|---|---|---|---|---|---|---|---|---|
| At risk | Normal | At risk | Normal | At risk | Normal | At risk | Normal | |
| N | 9 | 45 | 18 | 38 | 8 | 48 | 11 | 45 |
| Mean age (SD), years | 73 (8) | 70 (10) | 71 (8) | 65 (8)* | 70 (10) | 66 (8) | 68 (9) | 67 (8) |
| Gender (F/M) | 5/4 | 35/10 | 12/6 | 31/7 | 7/1 | 36/12 | 10/1 | 33/12 |
| Mean education (SD), years | 16 (6) | 16 (3) | 17 (4) | 15 (3) | 16 (4) | 16 (3) | 16 (4) | 16 (3) |
| BMI (normal/overweight/obese) | 3/6/0 | 17/19/9 | 3/10/5 | 17/12/9 | 4/3/1 | 16/19/13 | 5/3/3 | 15/19/11 |
| Diabetes (-/+) | 9/0 | 43/2 | 17/1 | 36/2 | 8/0 | 45/3 | 11/0 | 42/3 |
| Hypertension (-/+) | 7/2 | 24/21 | 8/10 | 23/15 | 4/4 | 27/21 | 6/5 | 25/20 |
| Heart problems (-/+) | 7/2 | 35/10 | 13/5 | 29/9 | 4/4 | 38/10 | 6/5 | 36/9 |
| Depression (-/+) | 9/0 | 43/2 | 18/0 | 36/2 | 8/0 | 46/2 | 10/1 | 44/1 |
| APOE ε4 (-/+) | 3/6 | 35/10* | 9/9 | 26/12 | 4/4 | 31/17 | 5/6 | 30/15 |
| AHA exercise group (-/+) | 9/0 | 34/11 | 17/1 | 29/9 | 8/0 | 38/10 | 11/0 | 35/10 |
| Mean Exercise Score (SD) | 1.7 (1.6) | 3.7 (4.3)* | 2.4 (2.3) | 3.7 (4.0) | 1.8 (1.6) | +3.5 (3.8)* | 1.9 (2.0) | +3.6 (3.8)* |
*
p < .05.
+
Non-significant trend only after controlling for age, gender and education.
BMI=Body Mass Index; AHA exercise group represents whether individuals met the American Heart Association's recommended exercise levels (see text for details) with + indicating those who met recommendations.