Table 1.

Inputs for the cost-utility model. Please see the supplemental material for additional reference material.

Variables	CAS	CEA	Range	Distribution
	base	base
	case	case
Beginning as well (vs. minor stroke, %)	46	46	0–1	Beta
Transition rates (%):
Death after a major stroke (case-fatality rate)	13.9	13.9	10.5–17.4	Beta
30-day
Death	0.62	1.26	0–5.1	Beta
Minor stroke	3.81	2.66	0–12.8	Beta
Major stroke	3.21	2.02	0–7.3	Beta
MI	0.64	1.31	0–12.8	Beta
Long-term
Death, excess, per year	1.5	0.96	0–44.6	Beta
Any stroke, per year	4.0	2.1	0–18	Beta
Proportion major stroke	0.3	0.3	0–0.75	Beta
Costs (2007$):
Hospitalization cost for MI	9,100	9,100	5,000– 15,000	Triangular
minor stroke	9,800	9,800	5,000– 15,000	Triangular
major stroke	10,500	10,500	5,000– 15,000	Triangular
			15,000
Continuing (per yr) - MI	4,500	4,500	3,500–5,500	Triangular
minor stroke	7,500	7,500	1,000– 15,000	Triangular
major stroke – first year	66,500	66,500	40–90,000	Triangular
major stroke – subsequent years	33,900	33,900	15–55,000	Triangular
Procedure	10,400	9,170	6,000– 15,000	Triangular
Clopidogrel	130
Utilities:
Myocardial infarction	0.88	0.88	0.65–1.0	Uniform
Minor stroke	0.65	0.65	0.5–0.9	Uniform
Major stroke	0.15	0.15	0–0.5	Uniform