TABLE 2.
Percentage of sphingolipid classes to total sphingolipid content
| Sphingolipids |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| SM | LacCer | HexCer | Cer | S1P/dhSph | Sph/dhSph | Cer1P | |||
| Male (n = 5) | Nonfasting | Serum | 85.3 ± 1.2 | 6.9 ± 1.4 | 3.8 ± 0.9 | 3.6 ± 0.9 | 0.40 ± 0.12 | 0.005 ± 0.001 | 0.08 ± 0.02 |
| Plasma EDTA | 85.7 ± 1.5 | 6.8 ± 1.2 | 3.8 ± 1.1 | 3.2 ± 0.7 | 0.21 ± 0.05* | 0.005 ± 0.001 | 0.24 ± 0.10* | ||
| Plasma citrate | 87.6 ± 1.2* | 5.6 ± 0.9 | 3.6 ± 0.9 | 2.9 ± 0.6 | 0.18 ± 0.03* | 0.005 ± 0.001 | 0.08 ± 0.04 | ||
| Plasma heparin | 86.8 ± 1.9 | 6.1 ± 1.2 | 3.6 ± 1.1 | 3.2 ± 0.6 | 0.20 ± 0.04* | 0.006 ± 0.000* | 0.06 ± 0.01* | ||
| Fasting | Serum | 88.5 ± 0.9† | 5.0 ± 0.5† | 3.2 ± 0.7 | 2.7 ± 0.5 | 0.38 ± 0.09 | 0.004 ± 0.001 | 0.18 ± 0.02† | |
| Plasma EDTA | 88.6 ± 1.0† | 5.1 ± 0.7† | 3.3 ± 0.7 | 2.7 ± 0.6 | 0.18 ± 0.04* | 0.004 ± 0.001 | 0.24 ± 0.01* | ||
| Plasma citrate | 89.8 ± 1.1† | 4.2 ± 0.6† | 3.4 ± 0.7 | 2.3 ± 0.5 | 0.15 ± 0.03* | 0.005 ± 0.001 | 0.14 ± 0.03† | ||
| Plasma heparin | 87.7 ± 1.3 | 4.9 ± 0.5 | 4.4 ± 1.0 | 2.7 ± 0.5 | 0.19 ± 0.02* | 0.006 ± 0.003 | 0.11 ± 0.02*† | ||
| Female (n = 5) | Nonfasting | Serum | 84.1 ± 1.7 | 8.6 ± 1.0 | 3.5 ± 0.3 | 3.2 ± 0.8 | 0.43 ± 0.13 | 0.004 ± 0.001 | 0.17 ± 0.04‡ |
| Plasma EDTA | 88.4 ± 1.6*‡ | 5.8 ± 1.2* | 2.9 ± 0.3* | 2.5 ± 0.6 | 0.20 ± 0.05* | 0.005 ± 0.001 | 0.18 ± 0.05 | ||
| Plasma citrate | 87.4 ± 1.4* | 6.4 ± 1.2* | 3.2 ± 0.5 | 2.7 ± 0.7 | 0.14 ± 0.01*‡ | 0.005 ± 0.001 | 0.07 ± 0.03* | ||
| Plasma heparin | 86.2 ± 2.2 | 7.4 ± 1.0 | 3.1 ± 0.7 | 2.9 ± 1.0 | 0.17 ± 0.03* | 0.006 ± 0.003 | 0.08 ± 0.02*‡ | ||
| Fasting | Serum | 88.6 ± 1.1† | 5.9 ± 1.2† | 2.8 ± 0.3† | 2.2 ± 0.5† | 0.29 ± 0.06† | 0.004 ± 0.001 | 0.23 ± 0.03†‡ | |
| Plasma EDTA | 89.8 ± 1.5 | 4.5 ± 0.8† | 2.7 ± 0.2 | 2.5 ± 0.6 | 0.14 ± 0.01*† | 0.004 ± 0.001 | 0.26 ± 0.03† | ||
| Plasma citrate | 89.3 ± 2.0 | 4.9 ± 1.3 | 3.4 ± 0.5* | 2.1 ± 0.4 | 0.13 ± 0.02* | 0.005 ± 0.001 | 0.15 ± 0.03*† | ||
| Plasma heparin | 88.7 ± 0.7† | 5.2 ± 0.4† | 3.4 ± 0.4* | 2.4 ± 0.7 | 0.15 ± 0.00*‡ | 0.005 ± 0.001 | 0.13 ± 0.04*† | ||
Values are mean ± SD. * Significantly different from serum within each fasting or nonfasting group, P < 0.05. † Significantly different from corresponding nonfasting serum, plasma-EDTA, -citrate, or -heparin within each gender group, P < 0.05. ‡ Significantly different from corresponding male fasting or nonfasting serum, plasma-EDTA, -citrate, or -heparin, P < 0.05.